Is Babassuamidopropalkonium Chloride Safe?
Babassuamidopropalkonium Chloride is a quaternary ammonium salt. It is created by a complex reaction starting with babassu fatty acids and adding amines, alkines, methyl iodide and then following up by treating it with silver oxide, water, and heat. It's used as a surfactant, conditioning agent and fabric softener.
All quaternary ammonium compounds carry risks.
Quaternary ammonium compounds can cause toxic effects all routes of exposure including inhalation, ingestion, dermal application and irrigation of body cavities. Exposure to diluted solutions can cause mild and self-limited irritation. Concentrated solutions of quaternary ammonium compounds are corrosive and can cause burns to the skin and the mucous membranes. They can produce systemic toxicity due to their curare-like properties. They can also cause allergic reactions. Mild to severe caustic burns of the skin and mucous membranes can occur depending on the agent and the concentration. Other signs may include: nausea, vomiting, abdominal pain, anxiety, restlessness, coma, convulsions, hypotension, cyanosis and apnoea due to respiratory muscle paralysis; death may occur within 1 or 3 hours after ingestion of concentrated solutions. Haemolysis and methaemoglobinemia have been reported infrequently.
Of course these effects are when in contact with the chemical at full-strength. However, you can see their potential toxicity.
Quaternary ammonium compounds like Babassuamidopropalkonium Chloride have also been found to potentially release carcinogens called nitrosamines in the presence of other chemicals (nitrostating agents).
Also quaternary ammonium compounds may be of relevance with respect to NOC formation, as may be deduced from reports on acute liver toxicity of combinations of nitrite and certain quaternary ammonium compounds (Maduagwu, 1985). Moreover, amine nitrosation by nitrite has been reported to be catalyzed in presence of the cationic surfactant decyltrimethylammonium bromide and other micelle forming agents (Okun et al, 1977), suggesting amine impurities in such surfactants being prone to enhanced nitrosation risk. ( Source)
Quaternary ammonium compounds are documented for the potential to be estrogen mimickers and decreased fertility in animal studies. ( Source) Quaternary ammonium compounds like Babassuamidopropalkonium Chloride have also been found to be toxic to mitochondria in cells. This may explain their hormone-disrupting activity. (Source)
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